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pentobarbital will reduce the level or result of ketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
If phenobarbital and doxycycline are administered concurrently, the scientific response to doxycycline needs to be monitored closely.
Barbiturates appear to improve the metabolism of exogenous corticosteroids in all probability throughout the induction of hepatic microsomal enzymes. Individuals stabilized on corticosteroid therapy may have to have dosage adjustments if barbiturates are extra to or withdrawn from their dosage regimen.
pentobarbital will reduce the extent or outcome of estradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can minimize panobinostat concentrations by ~70% and bring about procedure failure.
pentobarbital will reduce the level or impact of paclitaxel protein bound by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
pentobarbital will decrease the extent or outcome here of temsirolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the level or impact of tinidazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Contraindicated (one)pentobarbital will lower the level or influence of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with strong CYP3A4 inducers is not encouraged
pentobarbital will lessen the extent or outcome of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will lessen the level or result of copyright topical by affecting hepatic enzyme CYP2B6 metabolism. Slight/Significance Mysterious.
pentobarbital will decrease the level or influence of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or outcome of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir could be diminished if coadministered with sturdy CYP3A inducers and it is as a result contraindicated.